As Week 17 approaches, fantasy football owners face crucial decisions to secure championships. Key updates include the injury of tight end David Njoku, who is out against the Dolphins, potentially impacting lineup choices. Various sources provide start/sit advice for running backs, wide receivers, and defenses, with notable players such as Bo Nix and Tyjae Spears highlighted as must-start options. Additionally, expert rankings and bold predictions offer insights into matchups to target or avoid, emphasizing the importance of optimizing your roster for victory. As fantasy playoffs come to a close, owners should review updated rankings and waiver wire pickups to enhance their chances in this critical week.