The Department of Homeland Security has unveiled a groundbreaking framework designed for the safe and secure deployment of artificial intelligence in critical infrastructure sectors. This new guidance sets forth comprehensive rules aimed at ensuring the responsible application of AI technologies, responding to both domestic and international pressures regarding AI standards. With concerns about private data and military applications also addressed, this initiative may represent a significant milestone for U.S. AI policy, particularly as the Biden administration navigates the potential impact of future administrations on these evolving regulations.