The New England Patriots are making significant roster adjustments ahead of their Week 4 matchup against the San Francisco 49ers. They have signed cornerback Isaiah Bolden to bolster their defensive lineup, elevating several veterans to the active roster as they address injuries, including the significant loss of starting tackle Vederian Lowe, who has been ruled out for the game. While the Patriots are facing challenges with their offensive line, the 49ers are also looking to overcome a two-game skid and regain their momentum at home. Key players from both teams will be under scrutiny, with experts predicting an intriguing matchup, especially considering the Patriots' struggling offense against the formidable 49ers defense. Fans across the US will have the opportunity to watch the game on television, as it will be broadcasted in nearly half the country. As kickoff approaches, both teams are preparing for what could be a pivotal game in their respective seasons.