The San Francisco 49ers are grappling with significant injury issues as QB Brock Purdy has been ruled out for their upcoming game against the Tampa Bay Buccaneers due to a toe injury. Meanwhile, Mac Jones, expected to start, is listed as questionable with knee and oblique injuries. Despite these setbacks, the 49ers have confidence in Jones, who is currently managing his limitations in practice. As the team prepares for this crucial matchup against the Buccaneers, the uncertainty surrounding their quarterback situation has left fans on edge. The 49ers also noted that they are not alone in dealing with injuries, as the Buccaneers are facing similar issues.