A UPS cargo plane tragically crashed shortly after takeoff from Louisville Muhammad Ali International Airport, resulting in at least 7 fatalities and 11 injuries. Eyewitness accounts describe a massive fireball erupting as the plane went down, prompting emergency services to respond to the scene. The situation has escalated, leading to a shelter-in-place order for nearby residents. Authorities are investigating the incident, with officials confirming the death toll may rise. Video footage shows the dramatic moments of the crash, highlighting the catastrophic nature of the event.