As the Buffalo Bills prepare for their Week 13 clash against the San Francisco 49ers, the team continues to deal with significant injury updates. Tight end Dalton Kincaid has been ruled out due to a knee injury, leaving a gap in the offense. Meanwhile, linebacker Matt Milano, who has been sidelined, is trending in the right direction and could make his return to the field after recent practice participation. Coach Sean McDermott remains cautious, suggesting that while Milano is improving, his status for Sunday is still uncertain. Additionally, offensive lineman Spencer Brown is back, but wide receiver Keon Coleman is listed as questionable. The Bills are looking to navigate these injury challenges as they aim to compete effectively against a strong 49ers team.