The Indianapolis Colts are grappling with significant injury issues as they prepare for their upcoming game against the Denver Broncos. Offensive tackle Braden Smith has been placed on the reserve/non-football illness list, effectively ending his season. This development adds to the challenges as the Colts have also ruled out center Ryan Kelly and linebacker Jaylon Carlies for the game. Wide receiver Ashton Dulin has also been ruled out after non-participation in practice. With multiple key players unavailable, the Colts are facing a potential reshuffle of their offensive line for this crucial matchup against the Broncos.