As Week 10 of Fantasy Football unfolds, managers face crucial lineup decisions. Key recommendations include starting players like Michael Pittman and Jaxson Dart while being cautious with others such as Alvin Kamara and Kimani Vidal. The waiver wire remains active with top pickups like Colston Loveland and Alec Pierce gaining attention. Analysts emphasize the importance of matchups, particularly highlighting the Houston defense against the Jaguars. Furthermore, insights on streamers and must-start quarterbacks, along with the panic meter for underperforming stars, provide managers with the necessary tools to optimize their fantasy rosters this week.