A significant winter storm has led to severe driving conditions across Indiana, resulting in a major pileup involving at least 45 vehicles on the westbound I-70 in Vigo County. The overnight snow left roads slick and hazardous, prompting travel advisories in northeast Indiana and northwest Ohio. Authorities reported numerous accidents as snowfall continues, with I-70 closed due to cleanup efforts expected to take at least six hours. Despite the chaos, no major injuries have been reported. Residents are urged to avoid travel as conditions remain dangerous, with multiple reports of slide-offs and additional crashes throughout the region.