Significant challenges loom over leading Alzheimer’s projects and cancer research as funding cuts threaten critical ongoing studies. Researchers are grappling with layoffs and budget constraints following orders to eliminate billions in federal contracts. Despite a promising cancer breakthrough, the National Institutes of Health (NIH) faces setbacks, including delayed trials and the loss of essential research data. Advocacy efforts from survivors and scientists underscore the urgent need for sustained funding, as cuts could impede advancements in both Alzheimer’s and cancer treatment.