A UPS cargo plane crashed shortly after takeoff from Muhammad Ali International Airport in Louisville, Kentucky, resulting in at least seven confirmed deaths and eleven injuries. Eyewitness reports and dashcam footage vividly captured the horrific incident, which led to a massive fireball and extensive smoke as the aircraft burst into flames. The crash has prompted a shelter-in-place order and a thorough investigation into the causes, as officials fear that the death toll may rise. The UPS facility in Louisville is a major hub, with approximately 300 flights daily, highlighting the significant impact of this tragedy on the local community and operations.