Recent research has unveiled that humans may have begun using drugs as far back as 25,000 years ago, with scientists discovering the earliest evidence of habitual drug use in fossilized teeth found in Indonesia. The findings suggest that ancient foragers engaged in the consumption of mind-altering substances, such as betel nuts, indicating that the practice of using psychoactive drugs dates back much further than previously believed. These insights into the Ice Age origins of drug use highlight an intriguing aspect of human behavior, offering a glimpse into the cultural practices of early humans who used these substances long before known historical records.