U.S. stock futures have seen a significant decline as President Trump intensifies the threat of unilateral tariffs, causing jitters among investors. Wall Street futures are down with concerns surrounding escalating tensions in the Middle East, notably affecting companies like Boeing. The overall sentiment reflects a risk-off mood, as global markets retreat under the weight of trade uncertainties and geopolitical unrest, including rising nuclear concerns in Iran. Analysts indicate that the PPI inflation data, due to be released, is likely to further test market direction. As a result, major indices such as the Dow, S&P 500, and Nasdaq are expected to open lower, while Asian and European markets have also experienced declines. Traders remain on edge, eyeing any potential developments on trade policy and geopolitical tensions.