Significant lake effect snow is expected to impact the Great Lakes region this Thanksgiving, causing treacherous travel conditions. The National Weather Service has issued winter storm watches across multiple areas, with forecasts predicting heavy snow accumulations in upstate New York, including Central NY, the Mohawk Valley, and the Adirondacks. PennDOT has implemented vehicle restrictions due to hazardous driving conditions anticipated from gusty winds and snowfall. Snowfall projections indicate that regions north of I-80 in Pennsylvania could see between 3 to 7 inches of snow, while areas in New York may face up to 5 inches by Saturday morning. Many travelers are advised to prepare for severe weather and potential delays throughout the holiday weekend.