The Madre Fire in California has rapidly expanded to over 52,000 acres, making it the largest wildfire in the state this year. The blaze, fueled by hot and windy conditions, has prompted widespread evacuation orders, particularly in San Luis Obispo County. Highway 166 has been closed as firefighters battle the fire, which continues to grow in size despite their efforts. Air quality is a growing concern for nearby communities due to the smoke from the fire. Authorities are urging residents to evacuate and to stay informed on the evolving situation as firefighters work to contain the blaze.