As the New England Patriots gear up to face the San Francisco 49ers in Week 4 of the NFL season, they approach the game with an underdog mentality following a solid week of practice. The Patriots have made several roster moves, including promoting Sidy Sow to make his season debut while placing Alex Austin on injured reserve. This matchup comes with high stakes for both teams, as the 49ers aim to bounce back from recent struggles and are favored to win. Key players to watch include Rhamondre Stevenson for the Patriots and Brandon Aiyuk for the 49ers. Inactives include linebacker Anfernee Jennings, while veteran players have been elevated to the active roster. The game is set to start with television and live stream options readily available for fans. Analysis and expert predictions indicate a tough road ahead for New England, but the team hopes to capitalize on any weaknesses shown by the 49ers' defense.