A recent government-commissioned report has revealed significant gaps in the regulation of cannabis across the United States, urging federal health authorities to take a more active role in shaping public health policy related to marijuana. The study indicates that fragmented state and federal regulations pose health risks, prompting calls for clarification on the classification of hemp-derived cannabinoids under the Controlled Substances Act (CSA). Experts emphasize that the federal government should provide guidance to states with legalized marijuana, close regulatory loopholes, and promote public health campaigns to mitigate potential health issues associated with cannabis use. The National Academies are advocating for clearer federal leadership to address these concerns and ensure a cohesive approach to cannabis regulations.