In a significant move, a high-ranking official at the FDA has overruled agency scientists regarding the approval and broader use of COVID-19 vaccines. Documents reveal that the chief of the Center for Biologics Evaluation and Research (CBER), Dr. Prasad, restricted vaccine approvals despite recommendations from FDA reviewers advocating for a more inclusive label for Moderna’s next-generation COVID shot. Concerns have been raised around the potential harms of the vaccine, particularly for low-risk populations, prompting debate on whether the benefits of vaccination outweigh the risks. The actions taken by Prasad have sparked criticism within the agency, as he has continued to disregard expert advice in favor of more restrictive measures on the use of COVID-19 vaccinations.