A significant winter storm system is approaching, potentially disrupting Thanksgiving travel for millions this week. Forecasts indicate a mix of rain and snow as the coldest air of the season threatens the Northeast, Midwest, and Great Lakes regions. There are warnings for winter weather across 14 states, with some areas expecting up to 7 feet of snow, which could lead to travel headaches in cities like New York and New Jersey. Madison and Boston travelers are advised to prepare for turbulent weather, with accumulating lake-effect snow expected starting from Black Friday. As families make their holiday plans, the potential for storm-related delays could impact everything from local travel to events like the Macy’s parade, underscoring the need for travelers to stay informed about changing conditions.