The San Francisco 49ers have unveiled their 2025 regular season schedule, generating significant buzz in the NFL community. Set to open the season against the Seattle Seahawks, the team is optimistic about their chances, thanks to a favorable last-place schedule that positions them among the winners of the schedule release. Analysts project the 49ers might secure as many as 8 wins, with a mix of prime-time matchups and critical games that could influence their playoff aspirations. Expectations are high for stars like Brock Purdy and Christian McCaffrey to lead the charge, while fans are eager to see if the team can build momentum early in the season. With key stretches identified in the schedule and critical matchups that could decide the fate of the NFC West, the 49ers are gearing up for what they hope will be a memorable comeback year.