More than 1,000 current and former employees of the Department of Health and Human Services (HHS) have signed a letter demanding the resignation of Health Secretary Robert F. Kennedy Jr. The growing discontent among health professionals is fueled by accusations that Kennedy is endangering public health through controversial policies and misinformation, particularly regarding vaccination. Former directors of the CDC have voiced strong criticism, labeling Kennedy as a peril to national health and calling for urgent reforms to restore public trust in health institutions. With multiple medical groups joining the chorus for his resignation and the situation escalating, the turmoil at the CDC continues to garner significant attention and concern from both political and healthcare leaders.